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Electroconvulsive therapy or ketamine? Clinical factors affect outcomes


Patients with moderate to severe treatment-resistant depression (TRD) might have better symptom relief from ketamine infusions than from electroconvulsive therapy (ECT), but those with severe TRD could benefit more from ECT early in treatment, an analysis led by a UT Southwestern Medical Center researcher shows.

Diagnosing essential tremor after death helps families learn risk


A statistical tool designed to analyze 11 characteristics of postmortem brains reliably diagnosed a common neurodegenerative disease known as essential tremor (ET), a study led by researchers at UT Southwestern Medical Center and Columbia University shows.

New AI tool may help detect early signs of dementia


A novel speech analysis tool that uses artificial intelligence was highly accurate in detecting mild cognitive impairment and dementia in a Spanish-speaking population, according to research led by UT Southwestern Medical Center.

UTSW study sheds light on rare form of autism


A new study focused on the gene tied to a rare form of autism spectrum disorder (ASD) called FOXP1 syndrome offers hope that gene therapy might be able to help patients with this condition.

UTSW Research: Improved bladder cancer detection, tracking gamma waves, and more


Studies analyze blue light cystoscopy, irregularities in brain activity, the origins of abnormal bone formations, and HIV transcription.

Essential tremor triples dementia risk, UTSW study shows


Patients with a common movement disorder known as essential tremor (ET) developed dementia at three times the rate of similarly aged people in the general population, a study led by UT Southwestern Medical Center researchers shows.

Female zebra finches seek mate who sings one song just right


Humans aren’t the only living beings who find a singing voice attractive in the opposite sex – songbirds do too. For about a third of the approximately 4,000 songbird species that sing only one song, the features that make these tunes alluring to a potential mate have been a long-standing mystery.

Unraveling the mystery of misfolded proteins in the brain


Proteins known as oligomeric chaperones help suppress the formation of misshaped proteins that cause a variety of degenerative and neurodegenerative diseases, such as Alzheimer’s, Huntington’s, and Parkinson’s.

Gene therapy offers hope for giant axonal neuropathy patients


A gene therapy developed by researchers at UT Southwestern Medical Center for a rare disease called giant axonal neuropathy (GAN) was well tolerated in pediatric patients and showed clear benefits, a new study reports.

Nerve decompression shows promise for diabetic neuropathy patients


Surgical nerve decompression, used to treat conditions such as carpal tunnel syndrome and sciatica, could play a role in relieving the pain of diabetic neuropathy patients, researchers at UT Southwestern Medical Center found.