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Study implicates another gene in brain that causes weight gain
Mutations in a gene called OTP cause obesity by controlling the output of another gene already targeted by an anti-obesity drug, a study led by UT Southwestern Medical Center researchers shows.
UT Southwestern pharmacologists earn Hill Prize from TAMEST
David Mangelsdorf, Ph.D., Chair and Professor of Pharmacology and Professor of Biochemistry at UT Southwestern Medical Center, has been awarded the Hill Prize in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) in recognition of his long-standing research on orphan nuclear receptors – proteins in the cell nucleus that flip genes on and off and are triggered by unknown molecules.
‘Good’ cholesterol may protect against brain atrophy, dementia
High-density lipoprotein (HDL), or “good” cholesterol, may play a vital role in conserving healthy brain matter in middle-aged adults, UT Southwestern Medical Center researchers report.
New findings expand genetic knowledge of autism underpinnings
Hundreds of novel genetic variants across an ancestrally diverse cohort of 195 families, including 222 people with autism spectrum disorder (ASD), have been identified by researchers at UT Southwestern Medical Center, expanding the catalog of known mutations associated with ASD.
Program enhances stroke care at nearly 3,000 U.S. hospitals
A study led by a researcher at UT Southwestern Medical Center shows a national initiative significantly improved stroke outcomes for millions of patients over its first 20 years, enhancing quality of care and consistency at more than 2,800 U.S. hospitals including UTSW.
Combination therapy slows cognitive decline, research shows
A novel combination therapy slowed cognitive decline in elderly patients with a history of depression – a major risk factor for developing Alzheimer’s and other forms of dementia, a study led by UT Southwestern Medical Center’s new Chair and Professor of Psychiatry found.
UTSW study explores link between high school IQ and alcohol use
A person’s IQ during high school is predictive of alcohol consumption later in life, according to a study by UT Southwestern Medical Center researchers published in Alcohol and Alcoholism.
UTSW Research: Alcohol-associated liver disease, depression treatment, and more
Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren’t equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.
UTSW study reveals how key protein affects neuron structure
A protein called torsinA plays a key role in the early development of neurons, determining where nuclear pores are placed in the membrane that encloses the nucleus of nerve cells, a study led by UT Southwestern Medical Center researchers shows.
Natural grass may pose greater risk for football concussions
Young football players who sustained a head-to-ground concussion practicing or playing games on natural grass experienced more symptoms – and significantly higher severity – than those who suffered concussions on artificial turf, researchers at UT Southwestern Medical Center found.