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UTSW Research: Dementia risk, depression, and more
Tens of millions worldwide have dementia, neurodegenerative diseases that affect memory, thinking, and daily routines. Chronic kidney disease (CKD) has been identified as a risk factor for dementia and has been associated with dementia symptoms, such as cognitive decline and impairment. However, it has been unclear how severity of CKD might affect dementia risk.
Developmental ‘switch’ in brain may shape lifelong obesity risk
Researchers at UT Southwestern Medical Center have discovered that a crucial developmental process in the brain’s hypothalamus may influence how susceptible individuals are to obesity.
Study finds gaps in concussion reporting across Texas high schools
Fewer concussions were reported among Texas high school athletes and students in urban and lower-income districts than in higher-income suburban districts despite larger enrollments, UT Southwestern Medical Center researchers found in a study.
Adult survivors of childhood cancer at higher risk for meningiomas
Certain chemotherapies are associated with an increased long-term risk of subsequent tumors in survivors of childhood cancer, according to a study led by researchers at UT Southwestern Medical Center.
Birds’ songs may help unlock brain patterns behind speech
Like falling dominoes, a sequence of activity in an area of the zebra finch brain plays to completion once initiated, allowing these birds to produce their full courtship song, a study led by UT Southwestern Medical Center researchers shows.
Changes in circadian rhythms linked to higher dementia risk
Disruptions in patterns of daily activity and rest may provide early clues to heightened dementia risk, a study co-led by a UT Southwestern Medical Center scientist found.
UTSW researchers boost the power of CAR T cells to fight cancer
UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes engineered cancer-fighting immune cells behave more like stem cells, improving their therapeutic effectiveness.
UT Southwestern to open DFW’s first state behavioral health hospital this summer
UT Southwestern Medical Center has been selected to operate the new Texas Behavioral Health Center – the first state acute care behavioral health hospital in the Dallas-Fort Worth area – announcing plans to care for its first patients this summer.
Modified tau thwarts aggregation in neurodegenerative disease
A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its biological function while resisting aggregation, a pathological trait linked to neurodegenerative diseases called tauopathies.
State’s investment in cancer research has helped draw top talent to UTSW
Early in his career, Ralf Kittler, Ph.D., attracted the attention of academic leaders at UT Southwestern Medical Center with his studies of DNA transcription factors and their role in tumor growth and suppression.