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Imagine a day when...

Alzheimer’s disease is a preventable condition.
A drug can be administered to repair a brain injury.
Brain stimulation speeds recovery after a stroke.
Depression can be halted in its earliest stages with patient-specific therapies.

The Peter O’Donnell Jr. Brain Institute recognizes that in order to solve the most challenging brain diseases, our work must be multidisciplinary. To achieve this, we integrate and leverage the strengths of multiple independent departments, centers, and divisions at UT Southwestern Medical Center. By bringing together clinical and basic researchers in a comprehensive Institute, we are fostering collaborations and providing resources that set the stage for progress and discovery as we work toward our vision of a future without brain disease.

Latest News

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Field Reports from OBI

The inaugural Field Reports highlight stories that are changing how the world understands and treats the brain.

Read Reports

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Graduate Student Award Symposium

The O'Donnell Brain Institute will hold its inaugural Graduate Student Award Symposium on October 17-18, 2024. Selected applicants will deliver invited talks on their research.


Shawn McClintock

PNTRC Scientific Director

Shawn McClintock, Ph.D., Professor of Psychiatry, has been named the inaugural Scientific Director of the Perot Neuroscience Translational Research Center.

Director’s Message

William T. Dauer, M.D.
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Solving brain disease is going to take everyone working together – the person studying molecules in the lab, the clinician understanding a patient’s symptoms, the staff caring for the patient, and everyone in between. We’re committed to that collaborative journey and confident of the outcome.”

William T. Dauer, M.D.Director of the Peter O’Donnell Jr. Brain Institute

Removing Barriers Between
Discovery and Care

At the O’Donnell Brain Institute, researchers and clinicians work closely together, by design. Combining basic and translational research with advanced clinical care produces scientific breakthroughs that can move from the labs to patients in the clinic faster than ever.

Expertise and Innovation

The O’Donnell Brain Institute has assembled brain scientists, neurosurgeons, neurologists, psychiatrists, radiologists, and specialists in rehabilitative medicine.

Their common goal: Discover and implement new and better ways to treat major forms of brain and spine diseases, and perhaps even prevent them in the future.

Departments, Divisions, & Centers

Collaborative Partners